CHAMOT is a manufacturer of recombinant proteins and antibodies, with a professional R & D team to pursue higher quality. We specialize in the development and production of protein and antibody reagents and also provide a full range of reagent platform development services. We can offer contract research services in the field of biomedical study for the pharmaceutical, biotechnology, and medical device industries as well as for research organizations. We take into consideration all your needs without compromising on quality.

Protein Expression

Key service features:

• Using our exclusive protein expression technique, the expression success rate of the target recombinant proteins can increase to above 90%.
• Flexibility for clients’ requirements, and the small scale production could be executed before large scale production.
• We also provide other additional services such as endotoxin detection, bio-activity analytic platform, tag protein removal, protein subpackage and lyophilization.
• One-stop service from codon analysis to protein purification.

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Biacore™ Kinetics Analysis

What we can do:

• A versatile system, Biacore™ T200, for high quality characterization of molecular interactions
• A professional team to discuss thoroughly for high efficiency of service running
• Experienced experts to optimize the SPR methods as well as maintain superior precision
• Providing whole complete data set

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Peptide Synthesis

Key service features:

• Our experts will discuss with you and confirm your requirements.
• From crude to 98%, we provide different purity of products for clients’ options.
• From mg to g, we offer a flexible amount of the peptide product.
• We have a well-established platform to synthesize the peptide in a short period. (usually 2-4 weeks).
• We offer kinds of modification choices for your synthetic peptide.
• We have the expertise to help you acquire the peptide with 100% sequence accuracy.
• We will offer the MS and HPLC report for clients to understand the quality of synthetic peptide.

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PTMs Identification

Key service features:

• Compared to antibody based identification, LC-MS/MS is able to identify protein PTM efficiently, which enables you to understand the PTM sites of your target protein.
• Leadgene offers the experienced scientist to discuss the experimental details with you.
• We provide comprehensive data which support you to understand the components of protein samples.

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Monoclonal Antibody Development

Key service features:

• Our experts will offer professional analysis and suggestions for antigen design.
• Our capable project manager and scientists will support and discuss with you throughout the process.
• Flexibility to increase the number of immunized animals.
• The fee is flexible, dependent on each stage of the completed project.
• We provide affinity purification to improve the purity of desired antibodies.
• The antibody screening service can be customized according to the client’s requirements.

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Polyclonal Antibody Development

Key service features:

• Our experts will offer professional analysis and suggestion for antigen design.
• Our capable project manager and scientists will support and discuss with you personally throughout the process.
• Flexibility to increase the number of immunized animals.
• We provide professional affinity purification technology to increase the purity of antibody.

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Recombinant Antibody Production

Key service features:

• Professional antibody sequence evaluation and optimization.
• Various constant region backbone choices.
   Human: IgG1 or IgG4 S108P
   Mouse: IgG1, IgG2a or IgG2b
   Rabbit: IgG
• Small scale expression test depends on your requirements.
• Flexible choice of antibody expression level of cell culture volume.

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Gene Synthesis & Construction

Key service features:

• Our experts will discuss with you and confirm your requirements.
• We offer sequence optimization for free to help you achieve your gene synthesis needs.
• We have the expertise to help you acquire the gene construct with 100% sequence accuracy.
• We offer series of vectors for subcloning, depending on your experimental requirements.

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CDMO service

We promise:

• Traceability of raw materials under strict regulations
• Complete records on equipment maintenance and calibration
• Professional personnel training
• Warranty on batch-to-batch consistency
• Stringent QA control
• A quality management system certified for ISO 13485
• Stability monitor on product shelf-life

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