Small molecule compounds usually refer to organic compounds with a molecular weight of less than 900 daltons, which can penetrate the cell membrane and quickly diffuse into the cell to reach the target. Such small molecule compounds can be used as inhibitors, agonists/antagonists, modulators, etc., and are widely used in organoid culture, immunology, epigenetics, signaling pathway, tumor research and other fields.

Among them, the commonly used small molecule compounds in organoid culture are: Y-27632, A 83-01, SB-202190, Gastrin, Nicotinamide, CHIR 99021, Prostaglandin E2, etc.